14Oct/102
Why do plasma free fatty acids increase in the blood with prolonged exercise?
I am researching the central fatigue hypothesis which suggests that an increase in brain serotonin causes central fatigue. This is increased by a higher ratio of plasma free tryptophan to BCAAs and this is siad to occur because of an increase in FFAs as they compete for binding sites with the tryptophan but there is no explanation as to why FFAs increase due to exercise. Any ideas?
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October 14th, 2010 - 19:17
Fatty acids are source of energy for skeletal muscle and heart muscle (after the glucose sources have been used). Although I don’t have a reliable source, but I can only assume that during prolonged exercise its levels increase in blood because the body’s need for energy increases.
October 14th, 2010 - 19:17
Your statement as to free fatty acids increasing with exercise is open to some question. The the following research article:http://jap.physiology.org/cgi/content/abstract/19/3/489